The Bank of Botswana has 11 Departments and 1 Division, namely:
- Banking and Currency
- Banking Supervision
- Corporate and Legal Affairs
- Finance
- Financial Markets
- Human Resources
- Information Communications and Technology
- Internal Audit Services
- Payments and Settlement
- Protective Services
- Research and Financial Stability
- Procurement and Property Management Division
Each Head of Department/Division reports to either the Governor, Deputy Governor or the General Manager/General Counsel. Cooperatively, the Departments/Division ensure the smooth running of the Bank and the implementation of the Bank's mandate.